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Definition time! Let's talk about the N:C ratio

Definition time!

The N:C ratio is a term used to describe how much cytoplasm there is in a cell compared to how big or small the nucleus is.

Cells with a high N:C ratio have a small amount of...

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Don't forget about these cells that might show up in organ aspirates

It’s super important to recognize what mesothelial cells look like, because they can be easily mistaken for neoplastic epithelial cells if you’re not expecting them.

This is one way...

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These cells shouldn't be in a liver!

What are those eosinophils doing in there?

This was a liver aspirate from a dog with an enlarged liver.  There are tons of intermediate to large sized lymphocytes (not supposed to be in a...

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Hey hepatocytes...you're showing you're age...

Definition time! 

Lipofuscin is a neat little pigment that you can find in the cytoplasm of hepatocytes. It’s just a normal aging change, so no need to panic when you see it.

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Tip for aspirating large masses

It’s tempting to just aim for the center of masses when sampling, but it’s a good idea to sample multiple different areas in case the center is all necrotic material. This is especially...

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This is what Cushings livers look like

Ahhh, the Cushings liver  

This case fits in a nice little box tied up with a Cushings bow.

A 14 year old Yorkie presented with PU/PD. His liver was heterogenous and enlarged on abdominal...

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