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Cyto Coffeehouse Case Spotlight: Pleural effusion in a cat

Cyto Coffeehouse Member Case Spotlight Time! 


This case was posted by Sarah Dasher. This is pleural effusion from a 9 year old cat with a 6 week history of difficulty breathing.

This is large cell lymphoma! 🙀


The population we’re seeing here are large lymphocytes. You may notice their nuclei are a little wonky (not round) and they sometimes have cytoplasmic vacuoles. This is a good case to demonstrate how not every lymphoma case has classic nuclear morphology, and vacuoles sometimes are seen in the cytoplasm. 


Also, can you spot the mitotic figures? There are several…


Thanks for posting this great learning case, Sarah. These are excellent photos of the effusion!


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